Nplate® (romiplostim)
Quick links
No dietary restrictions1
Flexibility of individualised dosing (1–10 μg/kg)1
Once-weekly dosing1
1: Input patient weight in kg
2: Select Nplate® dose§
μg/kg3: Note total dose (µg) and injection volume (mL)
Patient’s Total Dose
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Injection Volume
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4: Determine Nplate® vial(s) required for single use.
Using your patient’s total dose and/or injection volume calculated in STEP 3, refer to the full Product Information to determine the appropriate vial required for single-use dose.
§The recommended starting dose for Nplate® is 1 µg/kg.1
The dosage calculation examples are provided solely for educational purposes.
| Examples | Patient’s Total Dose (μg) = patient’s weight (kg) x dose (μg/kg) |
Injection Volume (mL) = patient’s total dose ÷ 500 μg/mL |
| 55 kg patient @ 1 μg/kg | 55 kg x 1 μg/kg = 55 μg |
55 μg ÷ 500 μg/mL = 0.11 mL |
| 75 kg patient @ 1 μg/kg | 75 kg x 1 μg/kg = 75 μg |
75 μg ÷ 500 μg/mL = 0.15 mL |
| 95 kg patient @ 1 μg/kg | 95 kg x 1 μg/kg = 95 μg |
95 μg ÷ 500 μg/mL = 0.19 mL |
| Examples | Patient’s Total Dose (μg) = patient’s weight (kg) x dose (μg/kg) |
Injection Volume (mL) = patient’s total dose ÷ 500 μg/mL |
| 55 kg patient @ 2 μg/kg | 55 kg x 2 μg/kg = 110 μg |
110 μg ÷ 500 μg/mL = 0.22 mL |
| 75 kg patient @ 4 μg/kg | 75 kg x 4 μg/kg = 300 μg |
300 μg ÷ 500 μg/mL = 0.60 mL |
| 95 kg patient @ 6 μg/kg | 95 kg x 6 μg/kg = 570 μg |
570 μg ÷ 500 μg/mL = 1.14 mL |
CALCULATOR
If you would like to request hard copies of the Nplate dosing calculator, please email medinfo.JAPAC@amgen.com
Learning from what expert clinicians and leading ITP units have shared with us, we have created a simple 5-step process for you — designed to help make ITP management as quick, simple and effective as possible for you and your patients.
CALCULATOR
If you would like to request hard copies of the Nplate dosing calculator, please email medinfo.JAPAC@amgen.com
Reference: 1. Nplate® (romiplostim) Approved Product Information. www.amgen.com.au/Nplate.PI.
June 2022 AU-15229
This site is intended for Australian Healthcare Professionals only.
